Publication/Date
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Headline and Summary
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Forbes Magazine
Dec. 11, 2020
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Regular Dental Appointments Could Help Diagnose Type 2 Diabetes
Forbes article highlights how tests performed during a dental visit can help diagnose prediabetes and type 2 diabetes across the world.
Original Study: Clinical Journal of Periodontology
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Medscape
Nov. 10, 2020
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Does Periodontitis Affect the Treatment Response of Biologics in the Treatment of Rheumatoid Arthritis?
This study aimed to examine the relationship between the extent of periodontal disease and the treatment response to biologics in Rheumatoid Arthritis patients. It concluded that periodontal disease may undermine the effectiveness of this common form of arthritis treatment.
Source: Arthritis Research and Therapy
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Forbes Magazine
Nov. 2, 2020
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Gum Disease and Tooth Loss Linked To Development Of Precancerous Cells In The Gut
Past research has been inconclusive as to whether periodontal disease may increase colorectal cancer risk. This study, considered to be a "large well-designed, prospective study," provides stronger evidence that a link does exist.
Full Story: Forbes Magazine
Source: American Association for Cancer Research
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Genetic Engineering & Biotechnology News
Oct. 21, 2020
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The Missing Link That Connects Gum Disease to Inflammatory Diseases
Researchers at the University of Toronto studied the effect of a substance called "polymorphonuclear neutrophils," which can be found in abundance at inflammation sites, including teeth impacted by periodontal disease. They concluded that the ensuing hyperactive immune system response may contribute to the worsening of other inflammatory conditions.
Full Story: Genetic Engineering & Biotechnology News
Source: Sage Journals
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Dr. Bicuspid
Oct. 1, 2020
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Mouth pathogens may trigger oral squamous cell carcinoma
This study assessed the link between periodontal disease and oral cancer in mice. The purpose of this study was to test the hypothesis that key periodontal pathogens promote oral cancer, and that bacteriocin/nisin therapy may modulate these responses. The study concluded that the link exists, and that the therapy may be effective.
Full Story: Dr. Bicuspid
Source: PLOS Pathogens
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NADP SmartBrief
March 5, 2020
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Frequent tooth brushing may reduce diabetes risk
A study published in Diabetologia found that brushing teeth at least three times a day decreases the risk of developing type 2 diabetes. The findings, based on a cohort of 188,013 diabetes patients from South Korea, also revealed that the presence of periodontal disease and missing teeth were tied to the occurrence of new-onset diabetes after adjustments for demographics, smoking status, regular exercise, alcohol consumption, vascular risk factors, history of malignancy and laboratory findings.
Full Story: Physician's Briefing/HealthDay News (3/3)
Source: Diabetologia
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Center for Disease Control
Systemic Review, Volume 16
Sept. 26, 2019
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Current Knowledge on Correlations Between Highly Prevalent Dental Conditions and Chronic Diseases: An Umbrella Review
Studies have investigated the relationships between chronic systemic and dental conditions, but it remains unclear how such knowledge can be used in clinical practice. In this article, we provide an overview of existing systematic reviews, identifying and evaluating the most frequently reported dental–chronic disease correlations and common risk factors.
Source: CDC
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NADP SmartBrief
Oct. 25, 2020
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Study links poor oral health to higher risk of hypertension
People with periodontal disease are more likely than those with good oral health to have hypertension, and their blood pressure might not respond well to medication, according to a study published in Hypertension. Physicians and dentists should be aware of the association and monitor patients' blood pressure and oral health accordingly, lead author Davide Pietropaoli said.
Full Story: The Atlanta Journal-Constitution (free content) (10/23)
Source: Hypertension, American Heart Association, volume 72, No. 6
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NADP SmartBrief
Oct. 11, 2020
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Mouse study links chronic periodontitis to Alzheimer's risk
Researchers at the University of Illinois at Chicago found that mice chronically exposed to bacteria that cause chronic periodontitis for 22 weeks had greater levels of accumulated amyloid beta, increased brain inflammation and fewer intact neurons due to degeneration, which are common in patients with Alzheimer's disease, compared with mice not exposed to the pathogen. The research, published in PLOS ONE, "is the first study to show that exposure to the periodontal bacteria results in the formation of senile plaques that accelerate the development of neuropathology found in Alzheimer's patients," said Dr. Keiko Watanabe, a periodontics professor at the school's College of Dentistry and a co-author of the study.
Full Story: United Press International (10/4)
Source: PLOS ONE
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NADP SmartBrief
Oct. 1, 2020
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Study: People with psoriasis might need extra dental care
People with psoriasis might have an elevated risk for periodontitis, according to a study published in the Journal of Investigative Dermatology. Researchers found genetic, pathophysiologic and risk factors common to both conditions and recommended including regular periodontal exams in psoriasis-management protocols.
Full Story: DrBicuspid (free registration) (1/9)
Source: Journal of Investigative Dermatology, Jan. 2, 2019
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Mayo Clinic: Healthy LifeStyle
June 4, 2019
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Oral Health: A Window to Your Overall Health
Explores connection between oral and overall health. Lists following conditions that can be linked to oral health:
- Endocarditis
- Cardiovascular disease
- Pregnancy and birth complications
- Pneumonia
Lists conditions that might also affect oral health:
- Diabetes
- HIV/AIDS
- Osteoporosis
- Alzheimer's disease
Source: Mayo Clinic Staff. “Oral Health: A Window to Your Overall Health.” Mayo Clinic. Mayo Foundation for Medical Education & Research, June 4, 2019.
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NADP SmartBrief
May 1, 2019
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Pediatric dental infections linked with adult cardiovascular disease
Adults are 87% more likely than average to develop subclinical atherosclerosis if they had one of four signs of oral infection as children, and the risk rises to 95% in adults who had all four signs -- bleeding during dental exams, cavities, fillings and pocketing around teeth -- in childhood, according to research published in JAMA Network Open. Hypertension and high body mass index are also associated with poor pediatric oral health, which may be a cause of these health conditions or an indicator of poor nutrition or other causal factors, says Dr. Salim Virani, who wrote an accompanying editorial.
Full Story: Reuters (4/30)
Source: JAMA Network Open, online April 26, 2019, bit.ly/2IQMLk8
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NADP SmartBrief
Nov. 1, 2018
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Study links oral health to blood glucose levels in diabetes
Patients with type 2 diabetes reduced their HbA1C levels by 7 mmol/mol on average one year after receiving intensive treatment for gum disease, compared with those who received standard care consisting of teeth cleaning and polishing, according to a study in The Lancet Diabetes & Endocrinology. Researchers analyzed 264 diabetes patients with moderate to severe gum disease and noted that intensive periodontal treatment "is similar to the effect that's seen when people with type 2 diabetes are prescribed a second blood glucose lowering drug," said lead researcher Francesco D'Aiuto.
Full Story: Diabetes (UK) (10/26)
Source: The Lancet Diabetes & Endocrinology.
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